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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
6.67
Human Site:
S691
Identified Species:
13.33
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
S691
S
Q
I
E
K
R
R
S
Q
N
I
K
M
V
Q
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
S820
S
Q
I
E
K
R
R
S
Q
N
I
K
M
V
Q
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
E642
M
K
R
A
I
E
Q
E
S
Q
I
S
L
K
D
Dog
Lupus familis
XP_536002
930
105612
Q691
S
H
I
E
K
K
T
Q
N
I
K
V
V
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
S666
D
E
L
R
K
E
I
S
K
S
M
F
A
E
M
Rat
Rattus norvegicus
NP_001009535
919
103710
P687
N
I
K
I
T
K
I
P
F
S
M
E
N
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
K678
F
Y
G
V
S
D
L
K
E
I
L
G
A
V
L
Chicken
Gallus gallus
NP_001006508
916
103017
P683
P
V
K
V
V
T
V
P
F
S
L
S
A
C
R
Frog
Xenopus laevis
NP_001079545
925
103654
V687
S
K
P
P
I
S
S
V
Q
V
A
F
K
L
S
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
L679
S
S
V
Q
G
L
R
L
V
N
R
L
A
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
I545
I
R
L
L
Q
E
P
I
N
S
S
I
T
N
T
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
K702
E
L
E
R
L
F
R
K
E
D
F
G
R
M
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
26.6
N.A.
13.3
0
N.A.
6.6
0
13.3
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
40
N.A.
46.6
46.6
N.A.
20
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
0
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
9
0
0
0
0
9
% D
% Glu:
9
9
9
25
0
25
0
9
17
0
0
9
0
9
0
% E
% Phe:
9
0
0
0
0
9
0
0
17
0
9
17
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
9
25
9
17
0
17
9
0
17
25
9
0
0
9
% I
% Lys:
0
17
17
0
34
17
0
17
9
0
9
17
9
9
17
% K
% Leu:
0
9
17
9
9
9
9
9
0
0
17
9
9
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
17
0
17
9
9
% M
% Asn:
9
0
0
0
0
0
0
0
17
25
0
0
9
9
0
% N
% Pro:
9
0
9
9
0
0
9
17
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
9
9
0
9
9
25
9
0
0
0
9
17
% Q
% Arg:
0
9
9
17
0
17
34
0
0
0
9
0
9
0
9
% R
% Ser:
42
9
0
0
9
9
9
25
9
34
9
17
0
9
9
% S
% Thr:
0
0
0
0
9
9
9
0
0
0
0
0
9
0
9
% T
% Val:
0
9
9
17
9
0
9
9
9
9
0
9
9
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _